Study on the hypoglycemic effect of mango leaf extract grown in Son La

Abstract

Mango leaves were extracted by Soxhlet with 60% ethanol, the obtained solution was distilled to remove the solvent under reduced pressure. The results showed that when using
the maximum allowable dose, there were no dead mice. Experimenting on blood glucoselowering effects on diabetic white mice obtained the results: with a dose of 500 mg/kg giving the best therapeutic effect, even slightly better than the positive control drug gliclazide, the blood glucose level decreased immediately after three days. After 21 days reduced to 52.5% and brought the blood glucose index to normal. This is a new direction in the use of drugs of plant origin in general and Mango leaves in particular.