Outcomes evaluation of early transurethral enucleation of the prostate after transrectal ultrasound-guided prostate biopsy

Abstract

   Objective: This study aims to assess the safety and efficacy of transurethral enucleation of the prostate (TUEP) performed early after transrectal ultrasound- guided prostate biopsy.

   Methods: A prospective study consisted of 78 BPH/BPO patients with prostate volume > 40ml, divided into two groups: Group 1 (36 patients with prostate biopsy within 3 weeks), and Group 2 (42 patients without prostate biopsy). Perioperative and postoperative parameters were compared between the groups.

   Results: No significant differences were observed in patient distribution, energy modality, or preoperative characteristics between the two groups. The enucleation time was significantly longer in the biopsy group (65.69 ± 21.02 minutes vs. 55.83 ± 17.56 minutes, p=0.027). However, there were no significant differences in hemoglobin reduction, catheterization duration, or complication rates between the groups. At 1-month follow-up, both groups demonstrated significant improvements, with no statistically significant differences in lower urinary tract symptoms (IPSS, QoL), maximum urinary flow rate (Qmax), or postoperative prostate volume. Correlation analysis indicated that prostate volume, prior biopsy status, and the use of morcellator influenced operative time. Linear regression analysis revealed that prior biopsy increased operative time by an average of 10 minutes, while the use of a morcellator reduced it by 29 minutes.

   Conclusion: Early transurethral enucleation of the prostate after transrectal prostate biopsy is a feasible, safe, and effective procedure. A predictive regression model may help estimate surgical time based on prostate volume, biopsy history, and tissue processing techniques.

DOI: 10.59715/pntjmp.4.2.22