A review: phospholipase C zeta (PLCζ) impacts fertilisation and improves human-assisted reproductive technology
Keywords:
assisted reproductive technology, fertilisation, oocyte activation, phospholipase C zeta, sperm
Abstract
The change of concentration of intracellular Ca2+ oscillations leads to oocyte activation and preparation for early embryogenesis. Phospholipase C zeta (PLCζ) plays an essential role in fertilisation. Clinical reports have suggested a link between defective PLCζ and male infertility. In particular, oocyte activation deficiency was mentioned as the cause of failure in many cases of infertility treated ith intracytoplasmic sperm injection
điểm /
đánh giá
Published
2022-07-22
Section
KHOA HỌC Y - DƯỢC