Survey of the use of antibiotics in the treatments for hospital-acquired pneumonia at Gia Dinh People's Hospital in 2022

Abstract

     Hospital-acquired pneumonia (HAP) is often caused by multi-antibiotic resistant bacteria, and is associated with a high mortality rate. The project was conducted with the goal of surveying compliance of antibiotic use with IDSA/ATS 2016 guidelines in the treatment of HAP. The cross-sectional, descriptive, retrospective research focused on the medical records of patients diagnosed with HAP  Gia Dinh People's Hospital in 2022 with a sample size of 250 medical records. Results have shown that the average age of patients was (67.45 ± 15.8) years, with 54,4 % of which were male. Empirical initial antibiotics treatment showed that b-lactam was the most prescribed (82.5 %) which is consistent with the instructions, followed by piperacillin/tazobactam and levofloxacin (10 %). The main pathogens were found as multi-resistant Gram-negative bacteria (79.4 %), mostly A. baumannii (26.5 %). There were 95 patients undergoing antibiogram (38 %). After treating with antibiotics (usually colistin + ampicillin/sulbactam regimen (7,8 %). There was 73.4 % of regimens were used according to antibiogram. There was 68 % of patients were treated successfully. Overall,  the most commonly found pathogen  in HAP is highly resistant Gram-negative bacteria with. The most commonly used antibiotic group is b-lactam. The use of antibiotics is relatively consistent with the instructions.