Study on chemical composition of Ivy’s leaves (Hedera helix L.)

Abstract

   In Viet Nam, Ivy (Hedera helix L.) is usually used as a ornamental plant and there have not been many studies on chemical constituents, pharmacological effects as well as medicinal applications. This study contributes to clarify the chemical constituents of ivy to use it as medicine in the field of herbal medicine and traditional medicine. Ivy leaves were collected in December 2019 in Lang Son and compared its morphological characteristics with the available documents. Leaves were cleaned, dried in shade; 3 kg of dried leaves were extracted with ethanol 70 % using low-pressure technique to obtain 30 g cataplasm. By rapid column chromatography technique to obtain six fractions. The fraction 5 has some potential and been crystalized using reverse-phase chromatography C-18 to get four sub-fractions and identified two constituents as He-2 (0.15 g – Hederacoside C) l and He-3 (0.45 g – Rutin). Hederacoside C has effects of expectorant, cough suppressant and bronchial smooth muscle reduction. Rutin is commonly used as a vessel wall stabilizing element.