In vitro antioxydant and cytotoxic activities of alcohol and chloroform extract Helicteres hirsuta Lour. Sterculiaceae

Abstract

   Helicteres hirsuta Lour. Sterculiaceae is known as a type of medicine for cancer treatment, detoxification ... Recent research shows that the ability to fight free radicals as well as the ability to fight cancer of Helicteres hirsuta Lour. Sterculiaceae. This study was conducted to evaluate the ability of free radical scavenging and cytotoxic activities of alcohol extracts and chloroform extracts of Helicteres hirsuta Lour. Sterculiaceae. The results showed that the antioxidant activity of alcohol extracts (IC50 = 60.83μg/ml) was higher than that of chloroform extract (IC50 = 74.58μg/ml). However, HepG2 hepatotoxic activity of chloroform extracts (IC50 = 9.17μg/ml) was stronger than that of alcohol extract (IC50 = 19.96μg/ml). Thus, Helicteres hirsuta Lour. Sterculiaceae contains anti-oxidant and cytotoxic active ingredients.