SYNTHESIS OF CALIXARENE DERIVATIVES

Abstract

Accidents in the nuclear industry and nuclear terrorist attacks render the development of new decontamination strategies critical. Scientists have recently conducted intensive studies on p-tert-butylcalix[6]arene and its derivatives because of their ability to form complex with radioactive substances. This article presents the synthesis of compounds 2,4,6-triethylester-1,3,5-trimethoxy-p-tert-butylcalix[6]arene and 1,3,5-trimethoxy-2,4,6-tri (carboxylic acid)-p-tert-butylcalix[6]arene. This synthesis was based on the Williamson reaction using potassium carbonate as base. The structures of the synthesized compounds were determined by adopting IR, MS, 1H-NMR, 13C-NMR databases.