TOXIC PROPERTIES OF NON-POLAR EXTRACTS OF ARTEMISIA VULGARIS ON ARTEMIA SHRIMP LARVAE

Abstract

Artemisia vulgaris, also known as mugwort, is a herb that is widely available in Vietnam. Aside from its use as a vegetable, mugwort has been widely used in folk remedies to address common health issues such as menstruation regulation, cough and cold treatment, anorexia, acne reduction, and haemostasis. Various studies have been conducted on this object for biological effects such as anticancer, antioxidant, anti-diabetes, anti-bacteria, and anti-inflammation. A brine shrimp lethal assay was performed in two timelines of treatment exposure to detect bio-effects in different fractions of the extract. The extracts had a significant impact after 24 hours of exposure, with LC50 values of 183.60 ± 7.40; 164.50 ± 9.10; 264.80 ± 19.20 and 511.30 ± 31.10(µg/mL) for chloroform, n-hexane, ethyl acetate, and water, respectively.