Development of direct C-3 difluoromethylation reaction for application in synthesis of quinoline-related drugs
Abstract
Fluorine holds a prominent position within the realm of drug discovery and development, substantiated by its presence in approximately 25% of drugs approved by the US Food and Drug Administration (FDA). Consequently, the advancement of new fluorination reactions stands as a pivotal area in medicinal chemistry...
điểm /
đánh giá
Published
2024-03-15
Section
PHYSICAL SCIENCES