Pathological characteristics of distemper disease in dogs diagnosed and treated at the Veterinary clinic of Thai Nguyen University of Agriculture and Forestry

Abstract

This study aimed to study on some pathological characteristics in the dogs infected with distemper disease was carried out at the Veterinary clinic, Thai Nguyen University of Agriculture and Forestry. The studied results showed that all of the dogs infected with this disease had the clinical symptoms, of which 100% of the infected dogs presented several manifestations, such as: fever, anorexia, cheerless; 95.52% of the infected dogs exposed the sign of vomiting; 92.54% of those showed green nasal discharge, conjunctivitis;
91.04% of the infected dogs presented coffee-colored diarrhea; 80.60% of the infected dogs had coughing symptoms; 52.24% of the infected dogs appeared nodules and hyperkeratosis of the paw pads; 16.42% of the infected dogs had neurological symptoms. The gross lesions manifested pulmonary hemorrhage, edema, white necrotic nodules, hemorrhagic small intestine with thin-walled mucosa, swollen liver and kidney, hemorrhagic spleen with necrotic nodules at the peripheral area, swollen ganglions with dark red
hemorrhage, congestive brain, and flaccid heart with pericarditis. The histological lesions focused mainly in the lungs, intestines, lymph nodes. All of the examined samples had inflammatory cellular infiltration. The number of red blood cells and hemoglobin, white blood cells, neutrophils, eosinophils, basophils, monocytes of the dogs infected with canine distemper disease was lower than those of the healthy dogs. The proportion of neutrophils in the infected dogs increased in comparison with the healthy dogs.