POTENTIAL APPLICATION OF ANTIMICROBIAL PEPTIDE IN THE MANAGEMENT OF WOUND INFECTION

Abstract

Skin and soft tissue wounds usually account for a significant proportion of
disease patterns in most countries, including Vietnam, and tend to increase. Skin
lesions are often accompanied by fungal and bacterial superinfections. Therefore,
prevention and treatment face many difficulties, especially in the situation of
antibiotic resistance, unwanted effects of drugs and the influence of underlying
diseases leading to difficult wound healing. Recently, antimicrobial peptides
(AMPs for short) have been attracting much attention in developing new wound-
healing solutions with many advantages compared to conventional antibiotics. In
fact, many antibacterial peptides are already being put into clinical trials at
different phases. This review focuses on the potential application of antimicrobial
peptides in supporting wound healing management.