STUDY ON SYNTHESIS OF SOME BIS [3-ARYL-4-FORMYLSYDNONE N-(2’,3’,4’,6’-TETRA-O-ACETYL-β-D-GALATOPYRANOSYL) THIOSEMICARBAZONATO] ZINC(II) COMPLEXES

Abstract

Thiosemicarbazone is compound that can take part in to many different
reactions to form bioactive compounds. In the thiosemicarbazone molecule there
are two groups link, imine -CH=N- and thiuore -NHCSNH-. These two groups
have abylity of reaction and take part in to types of reations differently. By
reaction of thioure group with zinc acetate, the N-(2',3',4',6'-tetra-O-acetyl-β-Dgalactopyranosyl) 3-aryl-4-formylsydnone compounds are transformed into bis
[3-aryl-4-formylsydnone N-(2',3',4',6'-tetra-O-acetyl-β-D-galactopyranosyl)
thiosemicarbazone] Zn(II) new complexes. The structure of the complexes was
confirmed by IR, 1H-NMR, 13C-NMR, ESI-MS spectral data. The biological activity
of the complexes was determined by testing the antimicrobial effect by the MIC
minimum inhibitory concentration and exploring the antioxidat effect by the
DPPH free radical capture.