INITIAL RESEARCH ON PHYTOCHEMICAL SCREENING AND BIOCHEMICAL ACITIVITY OF ABELMOSCHUS MOSCHATUS IN THAI NGUYEN PROVINCE

Abstract

Vong vang (Abelmoschus moschatus) is a medicinal plant that has been widely used in Vietnamese folk
medicine. This study presents some initial preliminary research results on the chemical composition and
antibacterial ability of stem parts, leaves, and roots of Vong vang plants collected in Dai Tu, Thai Nguyen. Vong
Vang leaf extract exhibits better antibacterial activity than stem and root extract against all three bacteria:
Pseudomonas aeruginosa, Staphylococcus aureus and Escherichia coli. Vong vang leaf extract shows good
ability to inhibit the proliferation of gastric cancer (AGS) and liver cancer (HepG2) cells, IC50 were 27  3 and 35
 2 µg/mL, respectively. At concentration 100 µg/mL, the effectiveness of inhibiting AGS and HepG2 cancer cell
proliferation is 86.25  0.59 % and 87.30  1.44 %, respectively. These results are a reliable scientific basis for
folk remedies as well as the potential for application in the medical field of the Abelmoschus moschatus plant.