CHEMICAL CONSTITUENTS OF BLUMEA BALSAMIFERA

Abstract

Blumea balsamifera (L.) DC. (Asteraceae) has been used as traditional medicine for thousands of years
in China and Southeast Asia countries, such as Vietnam, Malaysia, Thailand, and Philippines. The
plant displayed various biological activities, such as antitumor, antifungal, radical-scavenging and
anti-obesity properties. Our chemical insvestigation of Blumea balsamifera plant collected in Hatinh
province led to the isolation of five compounds including cytochalasin H (1), trans-sinapaldehyde (2)
and blumeatin A-C (3-5). Their chemical structures were elucidated by NMR, MS spectral analysis and
comparison with reported literatures. Compounds cytochalasin H (1) and trans-sinapaldehyde (2) were
isolated for the first time from B. balsamifera.