STUDY ON INFLUENCE FACTORS OF SELF-ASSEMBLY PROCESS TO THE SIZE OF MICROSPHERE CHITOSAN

Abstract

   In this study, carboxylated chitosan was obtained by selective oxidation in TEMPO-NaClO-NaBr system. The variations of the oxidation were explored. The morphological changes during the self-assembly process were also studied. Optimum conditions, which affected the chitosan self-assembly, were founded.The oxidation of chitosan could selectively convert C6 hydroxyl groups into C6 carboxyl groups, and increase in the carboxyl content in chitosan. Then amino groups reacted with carboxyl groups under the effect of electrostatic force, and thus self-assembly chitosan sheets were produced.Keywords: TEMPO, chitosan, oxidation, self-assembly.