EVALUATION OF THE RESULT IN INTRA CYTOPLASMIC SPERM INJECTION IN WOMEN WHO INDICATED CRYOPRESERVATION OF OOCYTE

Abstract

In 1986, the first clinical pregnancy using cryopreserved oocytes was reported by Chen et al. Up to now, there have been different studies to evaluate the effectiveness of oocyte freezing in preserving fertility. In Vietnam, the oocyst freezing technique has been carried out since 2003, until now there have not been many research publications on frozen oocytes. The objectives of this study was to evaluate the result in intra cytoplasmic sperm injection  in women who indicated cryopreservation of oocyte at A Thai Nguyen Hospital, we used methods of oocyte retrieval, cryopreserved oocyte and thawing oocyte, and analyzing the effect of micro-injection on 174 vitrified oocytes and 117 fresh oocytes. The fertilization rate of the vitrified oocyte was 90.43%, the one of fresh oocyte was 80.48%. The rate of good day 5 embryo between cryopreserved and fresh oocyte was 37.7% and 44.06%, respectively. The rate of ongoing pregnancy of patients transfer embryos from the vitrified oocyte was 33.3%, the fresh oocyte was 41.2%. This study showed that the rate of fertilization and the proportion of day 3 embryo and day 5 embryo between the cryopreserved and the fresh oocytes were similar.