ASSESSMENT OF ANTIBACTERIAL ACTIVITY OF PORTULACA OLERACEA EXTRACT IN THAI NGUYEN

Abstract

Portulaca oleracea is a vegetable that grows in wet wild places in our country. Portulaca oleracea contains many proteins, sterols, carotenoids and polysaccharides. Furthermore, it has many vitamins (A, C, E, and some B-complexes) and minerals (Ca, Fe, Mn, P, and Se). So, Portulaca oleracea is used as food but also as a medicine. In traditional medicine, Portulaca oleracea is used as a medicine for diarrhea, acne, diuretic, and deworming. In this study, Portulaca oleracea extract was used to chemical composition determination by color reaction and evaluate antibacterial activity. After reflux extraction, 90 g of ethanol extract and 30 g of dichloromethane extract were collected. The results show that the ethanol extracts and dichloromethane extract of Portulaca oleracea have phenolic, alkaloid, flavonoid, steroid groups. Alcohol and dichloromethane extracts of Portulaca oleracea have strong antibacterial ability, in which dichloromethane extract concentration of 100 mg/mL has the best bactericidal ability. Research results show the potential of Portulaca oleracea to replace antibiotics in human disease prevention.