The combined value of shear wave elastography ultrasound and fine needle aspiration cytology in diagnosis breast cancer

Abstract

Objective: Describe characteristics of 2D ultrasound images and shear wave elastography (SWE) ultrasound breast tumor. Determinate the combined value of SWE ultrasound and fine needle aspiraton cytology (FNAC) in diagnosis breast cancer.

Subject and method: 79 female patients with breast tumors were assigned 2D and SWE ultrasound, measure shear wave velocity (SWV) internal tumor and peripheral tumor, classified according to ACR - BIRADS 2013. Patients were assigned FNAC ultrasound guided and histopathological biosy after surgery. Compare the result 2D, SWE ultrasound and FNAC with the result of histopathological biopsy after surgery to determine the combined value of SWE ultrasound and FNAC in diagnosis breast cancer.

Result: 79 patients with 37 benign breast tumors, 42 malignant breast tumors. Mean SWV of malignant breast tumors are lower than benign breast tumors (p < 0.01). Cutoff SWV in the differential diagnosis of benign and malignant breast tumor at peripheral tumor 2.25 m/s; internal tumor 5.1 m/s. SWE ultrasound combined with FNAC has high value in diagnosis breast cancer with Se = 97.6%, Sp = 94.6%, Acc = 96.2%, PPV = 95.3%, NPV = 97.2%, high concordance with histopathological result after surgery Kappa = 0.924.