In silico screening of alkaloids as potential inhibitors of epidermal growth factor receptor
Từ khóa:
alkaloid, cancer, epidermal growth factor receptor (EGFR), Lipinski’s rule, molecular docking.
Tóm tắt
The epidermal growth factor receptor (EGFR) belongs to the HER/erbB receptor tyrosine kinase (RTK) family, serving as a crucial target for cancer treatment. Anti-EGFR drugs, used as a primary treatment for patients with advanced EGFR gene mutations such as T790M, C797S, and L858R, have shown greater efficacy and safety compared to standard chemotherapy...
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đánh giá
Phát hành ngày
2023-09-15
Chuyên mục
LIFE SCIENCES