MOLECULAR IODINE FOR THE SYNTHESIS OF 2-ARYLQUINOXALINES

  • Huynh Van Tien
  • Bui Thu Ha
  • Nguyen Van Hoa
  • Truong Bach Chien
  • Hoang Xuan The
  • Nguyen Thi Anh Ngoc
Từ khóa: o-phenylenediamines; molecular iodine; acetophenones; quinoxalines; Csp3 -H bond functionalization

Tóm tắt

This study gave a new method to synthesize 2-arylquinoxalines from o-phenylenediamines and aryl methyl ketones. The reaction occurred via molecular iodine[1]promoted direct C(sp3 )-H bond functionalization of aryl methyl ketones under transition metal-free conditions. The utilities of this study are the (1) direct Csp3 -H bond functionalization, (2) inexpensive and abundant iodine source, (3) transition metal-catalyst free, and (4) different synthesis of 2-arylquinoxalines from common materials.

điểm /   đánh giá
Phát hành ngày
2022-10-19
In ra
Tập. 22 Số. 3 (2022): SỐ ĐẶC BIỆT
Chuyên mục
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