https://www.vjol.info.vn/index.php/TCPTHLS/issue/feedTạp chí Phân tích Hóa, Lý và Sinh học2024-03-20T03:12:29+07:00Nguyễn Thị Thanh Thảohoiphantichhoalysinhvn@gmail.comOpen Journal Systems<p><strong>Tạp chí của Hội Khoa học Kỹ thuật Phân tích Hóa, Lý và Sinh học</strong></p>https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92757NGHIÊN CỨU XÁC ĐỊNH TỔNG HOẠT ĐỘ PHÓNG XẠ ALPHA, BETA TRONG CÁC MẪU NƯỚC THẢI ĐÃ XỬ LÝ TỪ QUÁ TRÌNH CHẾ BIẾN CÁC LOẠI QUẶNG SA KHOÁNG2024-03-19T09:38:24+07:00Đoàn Thanh Sơnhoiphantichhoalysinhvn@gmail.comNgô Quang Huyhoiphantichhoalysinhvn@gmail.comLê Quốc Việthoiphantichhoalysinhvn@gmail.comĐỗ Thị Ánh Tuyếthoiphantichhoalysinhvn@gmail.comNgô Văn Tuyếnhoiphantichhoalysinhvn@gmail.comVương Hữu Anhhoiphantichhoalysinhvn@gmail.com<p>The determination of gross alpha and beta activities in waters with the low dissolved solid materials<br>can be easily done. However, for the treatment of liquid wastes containing high radioactivity from the beach <br>sand mineral processing, a large amount of chemicals have been introduced to form soluble salts, which are <br>mainly NaCl, that contributes to the decrease in performance, and in sensitivity of the measurement, <br>resulting in the inaccurate or even impossible determination of the gross alpha and beta activities. The <br>method of separating radioactive elements from the interfering salt background by co-precipitation using<br>BaRa(SO4)2, and Fe(OH)3 was performed in this paper. The study was carried out on treated waste samples <br>from the beach sand mineral processing. The results showed that the efficiency of the radioactive elements <br>separation when the alpha activity was from 3.5 Bq/L and the beta from 2 Bq/L reached up to 95% and then <br>we could easily determine the gross alpha and beta radioactivity in the separated fractions with high <br>stability and accuracy. Limit of detection with alpha and beta for treated waste water from the beach sand <br>mineral processing was 0.0074 Bq/L and 0.021 Bq/L, respectively.</p>2024-03-19T08:04:02+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92758NGHIÊN CỨU XÁC ĐỊNH CÁC THÀNH PHẦN HÓA HỌC CỦA HẠT SIM RỪNG PHÚ QUỐC2024-03-19T09:38:26+07:00Hồ Văn Hảihoiphantichhoalysinhvn@gmail.comPhùng Thị Tínhhoiphantichhoalysinhvn@gmail.comLê Văn Nhânhoiphantichhoalysinhvn@gmail.com<p>Rhodomyrtus tomentosa (Aiton) Hassk is a plant species belonging to the family Myrtaceae. It is <br>widely distributed and used as a rich-nutrient food and a traditional medicine in South and East South Asia <br>such as China, Thailand, Malaysia, and Vietnam. In Vietnam, the leaf, root, and fruits of R. tomentosa have <br>been used to nourish the blood system, against diarrhoea, cure stomach ailments, antiinflammatory. The <br>fruits of this plant are processed into wine, candy, syrup… The objective of the present study was to <br>investigate the phytochemical constituents of the methanol extract of the seeds of R. tomentosa using gas <br>chromatography–mass spectrometry (GC-MS). There were 31 phytochemicals detected in the methanol <br>extract of Rhodomyrtus tomentosa seeds, including: fatty acids and their esters (38.65%); pyrrogallols <br>(23.43%); terpenes, sterols and other aroma compounds. A variety of bioactive compounds was present in <br>the seeds of R. tomentosa such as 1,2,3-Benzenetriol (22.33%), 9,12-Octadecadienoic acid (Z,Z)- (19.87%), <br>n-Hexadecanoic acid (8.09%), Octadecanoic acid (2.96%), Vitamine E (2.94%), γ-Tocopherol (0.89%), γSitosterol (2.03%), Amyrin (1.78%), Cymene(1.45%), 5-Hydroxymethylfurfural (0.86%)…, which <br>possessed the ability to be antioxidant, antiinfectious, antiinflammatory, anticancer, antifungal, antiviral and <br>antibacterial, hypoglycemic, lipid-lowering, fat-reducing... This is the basis for developing applied research <br>using the extract of Rhodomyrtus tomentosa seeds in daily life as well as improving the economic value of <br>wild Rhodomyrtus tomentosa trees in Phu Quoc island district, Kien Giang province.</p>2024-03-19T08:06:32+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92759NGHIÊN CỨU THIẾT LẬP QUY TRÌNH PHÂN TÍCH PCBs TRONG MẪU TRẦM TÍCH BIỂN BẰNG PHƯƠNG PHÁP SẮC KÝ KHÍ DETECTOR CỘNG KẾT ĐIỆN TỬ (GC-ECD)2024-03-19T09:38:27+07:00Nguyễn Thị Hằnghoiphantichhoalysinhvn@gmail.comNguyễn Nho Lânhoiphantichhoalysinhvn@gmail.comNgô Thị Thu Thủyhoiphantichhoalysinhvn@gmail.comLưu Thị Thu Hoàhoiphantichhoalysinhvn@gmail.comNguyễn Thị Kim Dunghoiphantichhoalysinhvn@gmail.com<p>Polychlorinated Biphenyls (PCB) is one of 12 groups of Persistent Organic Pollutants (POPs) that the <br>Stockholm Convention regulates for safe management, emission reduction and progress towards complete <br>disposal since 2004. The use of PCBs in industry (e.g., capacitors and transformers, heat transfer and antihydraulic agents, explosion-proof additives, in paint resins, long-lasting pesticides, etc.) can lead to their <br>significant residues in environments such as soil, water and sediment. In this study, PCBs in the marine <br>sediment samples collected from the coastal area beside Dinh An, Tran De estuaries (Hau River) in Soc <br>Trang province was determined using gas chromatography with ECD detector. The study on selection of <br>sediment samples preparation was implemented for getting better recovery efficiency. The established <br>procedure for PCBs analysis showed that the detection limit of method (MDL) and the quantification limit of <br>method (MQL) of seven congeners were in the range of 0.051-0.060 µg/kg and 0.168-0.196 µg/kg, <br>respectively. The recovery was achieved from 70 to 120% with a relative standard deviation (RSD) lower <br>than 15%, and the relative error was about 10.3% with the analysis of a certified reference material (CRM). <br>The procedure for analysis of PCBs is thus sufficiently accurate, reliable and applicable to evaluate PCBs in <br>marine sediment samples. The content of PCBs in the above - mentioned samples ranged from 0.21 ± 0.02 to <br>57.22 ± 6.40 µg/kg.</p>2024-03-19T08:12:39+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92764THẨM ĐỊNH QUY TRÌNH ĐỊNH LƯỢNG THUỐC CHỐNG TĂNG HUYẾT ÁP AMLODIPINE BESYLATE DẠNG VIÊN NANG BẰNG PHƯƠNG PHÁP HPLC ĐẦU DÒ DAD2024-03-19T09:38:29+07:00Trần Quang Đệhoiphantichhoalysinhvn@gmail.comLê Hồng Tháihoiphantichhoalysinhvn@gmail.comNguyễn Cường Quốchoiphantichhoalysinhvn@gmail.comTrần Thanh Mếnhoiphantichhoalysinhvn@gmail.comNguyễn Hoàng Sơnhoiphantichhoalysinhvn@gmail.com<p>The aim of this study was to validate a protocol for the determination of amlodipine besylate in capsules <br>using the HPLC method with a DAD detector at a wavelength of 237 nm. The HPLC separation was carried <br>out using a C18 column (25 cm × 4,6 mm; 5 μm) and the mobile phase system was used as CH3OH and <br>solution pH 3,0 (60:40) belonging to isocratic elution mode. The results of the validation proved that the <br>method showed good selectivity, linearity with R2<br>of 0,9997, a low limit of detection (LOD) of 1,27 ppm, a <br>limit of quantification (LOQ) of 3,8 ppm, an accuracy of 100,02%, and a precision of the method (RSD) of <br>less than 2%. In particular, the verified method was also applied to determine the amount of amlodipine <br>besylate in three real samples on the market, and the results indicated that the content of amlodipine<br>besylate in all three preparations was above 94% and qualified as prescribed by the Vietnam <br>Pharmacopoeia V.</p>2024-03-19T08:17:21+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92766NGHIÊN CỨU TẠO ĐĨA PHỦ HAPTEN-BSA DÙNG CHO PHÂN TÍCH NHANH DIOXIN BẰNG XÉT NGHIỆM MIỄN DỊCH LIÊN KẾT ENZYME2024-03-19T09:38:30+07:00Đặng Phương Namhoiphantichhoalysinhvn@gmail.comNguyễn Văn Hoànghoiphantichhoalysinhvn@gmail.comPhạm Kiên Cườnghoiphantichhoalysinhvn@gmail.comLê Thị Phương Hoahoiphantichhoalysinhvn@gmail.comNguyễn Khánh Hoàng Việthoiphantichhoalysinhvn@gmail.com<p>Dioxin is one of the organic compounds that are difficult to decompose, causing environmental <br>pollution and long-term effects on human health. The most reliable method for dioxin analysis is highresolution gas chromatography-mass spectrometry (HRGC/HRMS), but requires long analysis time, modern <br>equipment, and high cost. Currently, immunoassay methods have been used to rapidly detect and screen for <br>dioxin contamination in food and the environment. In particular, competitive ELISA is a method with high <br>sensitivity, good signal amplification of low concentrations and can detect many different toxic congeners in <br>the dioxin group. First, the antigen (hapten-BSA) was immobilized on a plate at 4°C overnight. After that, <br>ELISA reaction was performed on the hapten-coated wells, at room temperature. The immobilization step of <br>hapten-BSA onto the plate makes it difficult to analyze in the field, requires strict conditions and prolongs <br>the analysis time. Therefore, the creation of coated plate with hapten-BSA needs to be investigated. In this <br>study, coated plate with hapten-BSA was created with a hapten-BSA concentration of 0.5 µg/mL, using 5% <br>sucrose as a preservative, BSA concentration of blocking buffer is 0.5% and with a TCDD detection <br>threshold of 10 ppt in 12 month of storage. The successful creation of the coated plate with hapten-BSA <br>shortens the analysis time to about 4-5 hours, which is convenient for analysis and get results in the field.</p>2024-03-19T08:20:28+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92767ĐÁNH GIÁ SỰ HẤP PHỤ ION Pb2+ TRONG DUNG DỊCH NƯỚC TRÊN VẬT LIỆU THAN BÙN ĐƯỢC HOẠT HÓA2024-03-19T09:38:31+07:00Nguyễn Thanh Tươihoiphantichhoalysinhvn@gmail.comBùi Thị Minh Nguyệthoiphantichhoalysinhvn@gmail.comHồ Sỹ Thắnghoiphantichhoalysinhvn@gmail.comHuỳnh Thị Ngọchoiphantichhoalysinhvn@gmail.comNguyễn Văn Hưnghoiphantichhoalysinhvn@gmail.com<p>In this study, peat was activated with H3PO4 at a concentration of 2.0 M and dried at 105oC for 6 hours. <br>The samples after synthesis are characterized by several methods such as EDX, XRD, SEM, BET and <br>FTIR. The adsorption properties of the materials were evaluated through the removal of Pb2+ ions in <br>aqueous solution. Material characteristics showed that the activated peat sample had a higher specific <br>surface area and porosity than the raw peat sample. The study showed that the experimental data of Pb2+<br>ion adsorption on activated peat were well described according to both Langmuir and Freundlich <br>isotherm models, however, the Langmuir isotherm model was more suitable. The activated peat material <br>had a maximum adsorption capacity qm = 33.33 mg/g. In addition, the study also showed that the <br>adsorption of Pb2+ ions on activated peat follows the pseudo-second-order model. From the above <br>research results, it shows that the adsorbent material from peat has great potential in remove heavy metal <br>ions in aqueous solution.</p>2024-03-19T08:23:38+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92768XÁC NHẬN GIÁ TRỊ SỬ DỤNG CỦA PHƯƠNG PHÁP UPLC/MS/MS ĐỂ PHÂN TÍCH HÀM LƯỢNG TINOPAL CBS-X TRONG GẠO2024-03-20T03:12:29+07:00Nguyễn Kiều Hưnghoiphantichhoalysinhvn@gmail.comLê Văn Cườnghoiphantichhoalysinhvn@gmail.comNguyễn Thu Hằnghoiphantichhoalysinhvn@gmail.comTrần Văn Lươnghoiphantichhoalysinhvn@gmail.com<p>A method based on ultra high performance liquid chromatography coupled with tandem mass spectrometry <br>(UPLC/MS/MS) as development for simple and rapid determination of the residues of tinopal CBS - X in <br>rice products. The sample were extracted by 4 % phosphoric acid in acetonitrile and then analyzed in <br>multiple reaction monitoring (MRM) mode. The mobile phase was composed of solvent A (water) and <br>solvent B (acetonitrile). Gradient program was performed as follows: 0 - 0.5 min, 80% A; 0.5 - 4.0 min, 20% <br>A and at initial condition. Total run time is 8 min. The flow rate was settled at 0.3 ml/min with an injection <br>volume of 10 μl. Under the optimized conditions, the linear range for tinopal CBS - X is 1.0 – 10 ng/g, the <br>linear correlation coefficients are more than 0.99. The limits of quantification of tinopal CBS - X are 2.20 <br>ng/g. The recoveries of tinopal CBS - X ranged from 93.50 % - 118.3 % with relative standard deviation <br>(RSD) between 0.96 – 12.06 %. The method was validated according to the Directive 2002/657/EC and <br>subsequently applied to 18 samples of rice products.</p>2024-03-19T00:00:00+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92770NGHIÊN CỨU THÀNH PHẦN HÓA HỌC VÀ HOẠT TÍNH SINH HỌC CỦA TINH DẦU LÁ VỐI (CLEISTOCALYX OPERCULATUS ROXB.) TRỒNG Ở TỈNH PHÚ THỌ2024-03-19T09:38:32+07:00Trần Thị Hằnghoiphantichhoalysinhvn@gmail.comQuách Thị Thanh Vânhoiphantichhoalysinhvn@gmail.comNguyễn Văn Sơnhoiphantichhoalysinhvn@gmail.com<p>The aim of this study was to determine chemical composition, and evaluate the antioxidant and antibacterial <br>activities of the essential oil from leaves of Cleistocalyx operculatus Roxb. grown in Phu Tho province. The <br>Gas chromatography-mass spectrometry (GC-MS) analyses of the essential oil of Cleistocalyx operculatus <br>Roxb. leaves led to the identification of 21 components. Its major constituents were (Z)--ocimene (60.59%), <br>(E)--ocimene (11.96%), -pinene (9.23%) and myrcene (6,22%). Antibacterial activity assays were <br>performed on the essential oil using the agar well method. The results indicated that the essential oil <br>showed antibacterial effects against Staphylococcus aureus, Pseudomonas aeruginosa and Candida<br>albicans, especially Pseudomonas aeruginosa antibacterial ability was much higher than that of cefotaxime <br>as an antibiotic. In the DPPH assay, the essential oil exhibited antioxidant activity with EC50 were 13828<br>g/mL.</p>2024-03-19T08:28:45+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92771ĐÁNH GIÁ THÀNH PHẦN POLYPHENOL VÀ HOẠT TÍNH ỨC CHẾ TYROSINASE CỦA CÁC DỊCH CHIẾT LÁ CALLISIA FRAGRANS2024-03-19T09:38:33+07:00Nguyễn Hoàng Khuê Túhoiphantichhoalysinhvn@gmail.comNguyễn Lâm Hải Myhoiphantichhoalysinhvn@gmail.comTrương Huỳnh Anh Vũhoiphantichhoalysinhvn@gmail.com<p>Callisia fragrans (C. fragrans) belongs to the family Commelinaceae and has wide applications in <br>the pharmaceutical field. The leaves were extracted by distillation in 40% methanol. The volatile extract (M) <br>was collected, while the extract remaining in the flask was fractionated with the obtained ethyl acetate <br>extract (Y) and the remaining extract after passing ethyl acetate (B). Total polyphenols (TPCs) of extracts in <br>(M), (Y) and (B) were determined spectrophotometrically using Folin Ciocalteu reagent, with Gallic acid <br>used as standard. The TPCs of (M), (Y) and (B) were determined as 4.7 ± 0.22 mg GAE/g, 17.91 ± 0.0031 <br>mg GAE/g, 47.11 ± 0.22 mg GAE/g dry weight, respectively. By liquid chromatography – mass spectrum, <br>gallic acid and 1-O-(E)-caffeoyl-4,6-di-O-galloyl-β-D-glucopyranose were detected in (B). Furthermore, <br>tyrosinase inhibition was detected in extract (B) by tyrosinase inhibition assay due to the highest TPC <br>content, using kojic acid as standard due to its tyrosinase inhibitory ability. Relative inhibition of (B) was <br>17.29% and IC50 was 64.47 ± 0.06 µg/mL, equivalent to 2/3 the potency of kojic acid. Research has also <br>succeeded in creating microcapsules containing TPC. The study on C. fragrans contribute to the <br>pharmaceutical field.</p>2024-03-19T08:31:04+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92773ĐÁNH GIÁ CHẤT LƯỢNG SÂM NON HÀN QUỐC ĐƯỢC NUÔI TRỒNG KHÍ CANH TẠI VIỆT NAM2024-03-19T09:38:34+07:00Ngô Việt Đứchoiphantichhoalysinhvn@gmail.comHoàng Lê Tuấn Anhhoiphantichhoalysinhvn@gmail.comNgô Văn Hiếuhoiphantichhoalysinhvn@gmail.comPhạm Văn Cônghoiphantichhoalysinhvn@gmail.comĐỗ Thị Thu Hiềnhoiphantichhoalysinhvn@gmail.comVũ Thị Tranghoiphantichhoalysinhvn@gmail.comNguyễn Văn Dânhoiphantichhoalysinhvn@gmail.comĐỗ Hoàng Thịnhhoiphantichhoalysinhvn@gmail.comDương Thị Thùy Vânhoiphantichhoalysinhvn@gmail.com<p>The objective of this study is to evaluate the growth and functional components of ginseng sprouts <br>aeroponically grown in Vietnam. One-year-old ginseng roots were used in a controlled-environmental <br>aeroponic system including, temperature, humidity, light, pH, and EC. The growth characteristics of ginseng <br>sprouts consisting of plant height, stem length, plant weight, and stem diameter were measured after 30 days <br>of transplanting. Furthermore, functional components (total saponin, total polysaccharide, and total <br>flavonoid) in root, leaf and stem were also extracted. Results showed that the plant height and stem length of <br>ginseng sprouts grown in Vietnam were higher than those grown in South Korea. The content of saponin <br>and flavonoid in the leaf and stem was higher than that in the root, whereas the content of polysaccharides<br>in the leaf and stem was lower than that in the root. Additionally, the content of ginsenosides (e.g. Rg1, Re, <br>Rf, Rb1) in ginseng sprouts grown in Vietnam was lower than those grown in South Korea in both <br>traditional farming and aeroponical methods.</p>2024-03-19T08:34:35+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92775TỔNG HỢP, TÍNH CHẤT CÁC PHỨC CHẤT CỦA Tb(III), Dy(III), Yb(III) VỚI HỖN HỢP PHỐI TỬ BENZOIC VÀ 2,2’-DIPYRIDINE-N-OXIDE2024-03-19T09:38:35+07:00Nguyễn Thị Hiền Lanhoiphantichhoalysinhvn@gmail.comNguyễn Thị Tố Loanhoiphantichhoalysinhvn@gmail.com<p>This paper presents the synthesis of several complexes of Ln (III) (Ln: Tb, Dy, Yb) with mixed ligands <br>(benzo c and 2,2’-dipyridine-N-oxide). They are represented by the general formula of <br>Ln(Benz)2(DipyO)(H2O)2 (Ln: Tb, Dy, Yb; Benz-<br>: Benzoate, D p O: 2,2’-dipyridine-N-oxide). The <br>characterization of these complexes has been studied by IR, thermal analysis, mass, and emission <br>spectroscopy approaches. The results from IR spectroscopy suggested that complexes had been synthesized <br>successfully, and the coordination modes of the ligands to Ln(III) centres had been investigated by IR <br>spectroscopy. Mass spectroscopy findings showed that the synthesized complexes were monomers and <br>that they are stable. In addition, thermal analysis indicates that they are all quite stable to heat. The <br>emission spectra of the Tb(Benz)2(DipyO)(H2O)2 displayed three bands arising from the <br>5D4 → 7F5 dominant transition located at 545 nm, the weaker 5D4 → 7F6, <br>5D4 → 7F4 transitions located at <br>490 and 587 nm, respectively. The emission spectra of the Yb(Benz)2(DipyO)(H2O)2 displayed one band at <br>452 nm, meaning the 2F5/2→2<br>I7/2 energy level of Yb3+ was observed. The results of our study demonstrated<br>that these complexes exhibited room-temperature photoluminescence.</p>2024-03-19T08:37:29+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92776NGHIÊN CỨU TỔNG HỢP VẬT LIỆU XÚC TÁC QUANG CuO/UiO-66-NO2 ỨNG DỤNG XỬ LÝ CHẤT HỮU CƠ TRONG NƯỚC2024-03-19T09:38:35+07:00Trịnh Lê Thiệnhoiphantichhoalysinhvn@gmail.comĐinh Thị Hiênhoiphantichhoalysinhvn@gmail.comPhùng Thị Ngọchoiphantichhoalysinhvn@gmail.comLê Thanh Sơnhoiphantichhoalysinhvn@gmail.comTrịnh Xuân Đạihoiphantichhoalysinhvn@gmail.com<p>CuO/UiO-66-NO2 composite photocatalysts were successfully synthesized. The as-fabricated samples were <br>characterized by XRD, FT-IR, and UV-Vis DRS techniques. The photocatalytic activity of the materials was <br>evaluated by the decomposition of methylene blue (MB) under visible light. The influence of several factors <br>such as pH of solution and dosage of the catalyst on the photodegradation was studied. The optimum <br>conditions for the synthesis of the catalyst were also determined. Under optimal conditions, it was found that <br>100% of MB was removed due to the adsorption in darkness and the degradation in visible light illumination <br>within 200 min. The kinetics of the photocatalytic process were investigated and compared with pseudofirst-order and pseudo-second-order. The experiment data revealed that the kinetics of the photodegradation <br>fitted with the pseudo-first-order model and relatively fitted with the pseudo-second-order.</p>2024-03-19T08:40:28+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92779TỔNG HỢP, TÍNH CHẤT PHÁT QUANG CỦA CÁC PHỨC CHẤT TẠO BỞI Nd3+, Sm3+, Eu3+ VỚI HỖN HỢP PHỐI TỬ SALICYLIC VÀ 2,2’-DIPYRIDINE-N-OXIDE2024-03-19T09:38:36+07:00Nguyễn Thị Hiền Lanhoiphantichhoalysinhvn@gmail.comNguyễn Thị Tố Loanhoiphantichhoalysinhvn@gmail.com<p>In this paper, the luminescent properties of three synthesis complexes of Ln (III) (Ln: Nd, Sm, Eu) with mixed <br>l nds (s l l nd 2,2’-dipyridine-N-oxide) are described. The complexes correspond to their general <br>formula of Ln(Sal)2(DipyO)(H2O)2 (Ln: Nd, Eu; Sal-<br>: l l , D p O: 2,2’-dipyridine-N-oxide) and <br>Sm(Sal)2(DipyO). The products were characterized by IR, thermal analysis, mass, and emission <br>spectroscopy. The findings from IR spectroscopy suggested that complexes had been synthesized <br>successfully, in which three of them consisted of neutral monomeric molecules. The thermal analysis <br>indicated that they were all quite stable to heat. The luminescent spectra of the Eu(Sal)2(DipyO)(H2O)2<br>displayed five bands arising from the 5D0 –<br>7F2 dominant transition located at 614 nm, whereas the <br>weaker 5D0 –<br>7F1, <br>5D0 –<br>7F4 transitions located at 592 and 700 nm, respectively. Notably, the weakest 5D0 –<br>7F0, <br>5D0 –<br>7F3 transitions were located at 579, 652 nm, respectively. The luminescent spectra of the <br>Sm(Sal)2(DipyO) displayed three weak bands at 561, 598, and 645 nm, arising from 4G5/2 –<br>6H5/2,<br>4G5/2 –<br>6H7/2,<br>4G5/2 –<br>6H9/2 transitions. These complexes demonstrated photoluminescence under UV light at room <br>temperature.</p>2024-03-19T08:42:55+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92780TỔNG HỢP, CẤU TRÚC VÀ KHẢ NĂNG PHÁT HUỲNH QUANG CỦA MỘT SỐ PHỨC CHẤT ZINC(II)-SALOPHEN CHỨA DẪN XUẤT 2- HYDROXY-1-NAPHTHALDEHYDE2024-03-19T09:38:36+07:00Ninh Thị Minh Gianghoiphantichhoalysinhvn@gmail.comPhan Thị Ngọc Ánhhoiphantichhoalysinhvn@gmail.comPhạm Văn Thốnghoiphantichhoalysinhvn@gmail.comPhạm Thị Minh Thảohoiphantichhoalysinhvn@gmail.comLê Thị Hồng Hảihoiphantichhoalysinhvn@gmail.com<p>Five complexes of Zn(II) were synthesized by reaction between Zn(CH3COO)2.2H2O with 2-hydroxy-1-<br>naphthaldehyde and the derivations of 1,2-phenylenediamine. Their structures were characterized by IR, <br>ESI-MS and 1H NMR spectroscopy. The results showed that in these complexes, the molar ratios of Zn(II) <br>and the ligands are 1:1, Zn(II) is bound to the ligands through O and Nimine. Studies on the optical properties <br>of the complexes showed that the complexes in solid form emitted luminescence stronger than in solution. <br>When changing the substituent group on phenylene, the emission wavelengths of the complexes did not <br>change much, but the emission intensity changed in the order of substituents Br > H > F > Me > Cl (for <br>solid form) and Cl > Br> F > Me > H (for solution).</p>2024-03-19T08:45:59+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92785TỔNG HỢP, KHẢO SÁT TÍNH CHẤT QUANG VÀ HOẠT TÍNH XÚC TÁC QUANG CỦA VẬT LIỆU NANO CeO2:0,04Sm3+ , xEu3+2024-03-19T09:38:37+07:00Nguyễn Văn Hảihoiphantichhoalysinhvn@gmail.comNguyễn Thị Khánh Linhhoiphantichhoalysinhvn@gmail.comĐinh Thị Hiềnhoiphantichhoalysinhvn@gmail.comNguyễn Thị Anh Vuihoiphantichhoalysinhvn@gmail.comHoàng Như Vânhoiphantichhoalysinhvn@gmail.com<p>In this work, Sm3+/Eu3+<br>co-dopped CeO2 phosphor was synthesized through sol-gel method combined with <br>temperature calcination at 600℃. The crystal structure of powders was characterized by X-ray diffraction, <br>and it revealed that all studied samples were single-phase with the cubic fluorite-type structure and space <br>group Fm<br>3<br>m. The scanning electron microscopy (SEM), diffuse reflectance spectroscopy (DRS) and <br>photoluminescence (PL) spectra were employed to characterize the samples. The photoluminescence <br>measurements displayed that all the samples had excellent optical properties at room temperature. Under <br>404 nm excitation, the CeO2: Sm3+ exhibited typical peaks at 567, 604, and 653 nm corresponding to <br>transitions 4G5/2→6HJ (J = 5/2, 7/2, 9/2) of Sm3+. Meanwhile, CeO2:0,04Sm3+, xEu3+ phosphors exhibited<br>strong orange-red emission both Sm3+ and Eu3+. The photocatalytic performance of CeO2:0,04Sm3+<br>, xEu3+<br>nanocomposites was tested under ultraviolet irradiation on an aqueous solution of methylene blue (MB) dye <br>using an UV-C lamp. The degree of degradation was monitored by absorption spectroscopy. The <br>photocatalytic degradation efficiency of CeO2:0,04Sm3+<br>, 0,04Eu3+ was above 95% within only 90 min of <br>irradiation.</p>2024-03-19T08:56:34+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92787CHẾ TẠO VẬT LIỆU ĐIỆN CỰC DƯƠNG (NH4)0,5V2O5 DẠNG THANH ĐỊNH HƯỚNG ỨNG DỤNG CHO ĐIỆN CỰC DƯƠNG TRONG ẮC QUY NATRI – ION2024-03-19T09:38:38+07:00Huỳnh Lê Thanh Nguyênhoiphantichhoalysinhvn@gmail.comNguyễn Thị Hồng Ngưhoiphantichhoalysinhvn@gmail.comPhan Thị Ánh Hồnghoiphantichhoalysinhvn@gmail.comNguyễn Thu Thảohoiphantichhoalysinhvn@gmail.comNguyễn Thị Thu Tranghoiphantichhoalysinhvn@gmail.comNguyễn Hoàng Anhhoiphantichhoalysinhvn@gmail.comĐào Anh Tuấnhoiphantichhoalysinhvn@gmail.comNguyễn Thái Hoànghoiphantichhoalysinhvn@gmail.comLê Viết Hảihoiphantichhoalysinhvn@gmail.com<p>Sodium-ion batteries (SIBs) have gathered considerable attention as a potential alternative to lithium-ion <br>batteries (LIBs), due to their abundant sodium resources, cost-effectiveness, and safety. However, a <br>significant challenge in SIBs development lies in identifying high-performance cathode materials with <br>exceptional rate capability and long-term cycling stability. This work explores the potential of (NH4)0.5V2O5<br>as a promising cathode candidate for SIBs. The layered structural (NH4)0.5V2O5 was synthesized by <br>hydrothermal method with the precursors V2O5, NH3 solution and HCOOH at 200oC for 24 hours. The <br>structural and morphological properties were investigated by X-ray diffraction (XRD), scanning electron <br>microscopy (SEM) and Raman scattering spectroscopy. (NH4)0.5V2O5 demonstrated reversible intercalation <br>of Na+<br>ion with a specific capacity of 95 mAh.g-1<br>at rate C/5 in potential 1.5-4 V (vs. Na+<br>/Na) thus <br>highlighting its potential as a high-performance SIBs cathode material.</p>2024-03-19T08:59:48+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92791CHẾ VẬT LIỆU NANO CARBON TỪ THAN CỐC ĐỊNH HƯỚNG ỨNG DỤNG LÀM ANODE TRONG PIN Li-ION2024-03-19T09:38:40+07:00Đỗ Trà Hươnghoiphantichhoalysinhvn@gmail.comNguyễn Thị Ngahoiphantichhoalysinhvn@gmail.comNguyễn Văn Túhoiphantichhoalysinhvn@gmail.comNguyễn Quốc Dũnghoiphantichhoalysinhvn@gmail.com<p>Successfully fabricated porous carbon (CDC) nanomaterials from coke (CD) by Hummer method. The <br>fabricated nanomaterials are porous, with an average size of 30 - 40 nm. CDC electrode works well, stably <br>with capacitance retention of 74.7% after 1000 cycles. The constant current discharge method determined <br>the CDC specific capacitance to be 118 F/g corresponding to a current density of 0.01 A. The specific <br>capacitance decreased with increasing current density. CDC electrodes conducted electricity well. The <br>charge transfer resistance was very small. The results on the electrochemical properties of the material <br>showed that the energy storage capacity of the CDC material was good and stable.</p>2024-03-19T09:07:26+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92794NGHIÊN CỨU CHẾ TẠO HỆ VI KIM VẬT LIỆU POLYVINYLACOHOL BẰNG PHƯƠNG PHÁP KHẮC LASER TẠO KHUÔN2024-03-19T09:38:40+07:00Đỗ Thị Mỹ Hạnhhoiphantichhoalysinhvn@gmail.comPhạm Thu Uyênhoiphantichhoalysinhvn@gmail.comTrần Thanh Phươnghoiphantichhoalysinhvn@gmail.comNguyễn Thành Dươnghoiphantichhoalysinhvn@gmail.com<p>Microneedles (MN) offer an attractive, painless, and minimally invasive approach for drug delivery through <br>the skin. In this study, we describe a method for fabricating MN molds with controlled microstructures. <br>Microfabrication using laser ablation was employed to create patterns on the surface of PDMS sheets to <br>obtain MN molds, which were then replicated twice to produce PDMS molds and used with PVA material <br>for micro-needle fabrication. During the fabrication process, the microstructure of the MN molds was <br>controlled by varying laser parameters. The resulting MNs produced from these molds had dimensions of <br>approximately 1500 µm and could withstand forces ranging from 0.77 N to 0.93 N. Additionally, different <br>concentrations of PVA were investigated to determine the optimal conditions for fabricating micro-needle <br>systems with suitable mechanical properties. The study also assessed the characteristics of the microneedle <br>system, such as durability and effective drug delivery capability. The results demonstrated that at a PVA <br>concentration of 10%, the microneedles exhibited the best characteristics. The findings have shown the <br>feasibility of using PVA microneedles for drug distribution, offering a promising solution to address the <br>limitations of conventional drug delivery methods.</p>2024-03-19T09:09:38+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92795NGHIÊN CỨU CHẾ TẠO THIẾT BỊ VI LƯU GIÚP PHÂN LẬP EXOSOME TỪ MÔI TRƯỜNG ĐỒNG NUÔI CẤY TẾ BÀO UNG THƯ VÀ TẾ BÀO THÀNH MẠCH MÁU2024-03-19T09:38:41+07:00Nguyễn Thị Phương Ngahoiphantichhoalysinhvn@gmail.comTrịnh Văn Giáphoiphantichhoalysinhvn@gmail.comNguyễn Thành Dươnghoiphantichhoalysinhvn@gmail.com<p>The angiogenesis, the formation of new blood vessels, is crucial for nourishing and developing cells as well <br>as restoring the damaged area. In cancer, angiogenesis plays a crucial role by promoting the formation of <br>new blood vessels to feed cancer cells. These cells actively release signals that stimulate surrounding tissues <br>to initiate and facilitate the process of angiogenesis. Exosomes, extracellular vesicles isolated from cancer <br>cells, have been identified as a precursor for understanding the mechanism of angiogenesis and developing <br>new cancer treatments. Therefore, the evaluation of exosome formation, properties, and the application of <br>exosome as anti-angiogenic drugs carrier for cancer treatment has been widely interested. The main<br>purpose of this research is to fabricate a microfluidics device for co-culturing cancer cells and blood vessel <br>cells, in order to isolate and identify exosome characteristics and their effects on the development of <br>HUVEC cells. In this study, we fabricated a microfluidic device that can be cultured simultaneously with <br>two types of cells from commercially available materials - PMMA machined by laser engraving and PEGDA<br>hydrogel. The microfluidic device consisted of 3 layers, including 2 layers of PMMA (24 x 50 mm) and a <br>layer of cover glass. The isolated exosome form HepG2 cells had the average size around 65.4 nm by <br>dynamic light scatering (DLS) measurement. Further, HUVEC cells can develop faster at a rate of about 2 <br>times with the present of exosomes from HeG2 cells than single cell culture. Thus, the device is a promising <br>approach to future cancer treatment with wide range of applications.</p>2024-03-19T09:12:41+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92797KHẢO SÁT KHẢ NĂNG TÍCH LŨY ĐỒNG TỪ ĐẤT TRỒNG VÀ NGUY CƠ RỦI RO SỨC KHỎE KHI SỬ DỤNG MỘT SỐ LOẠI THẢO MỘC TRỒNG TRÊN ĐẤT Ô NHIỄM2024-03-19T09:38:42+07:00Lê Thị Thanh Trânhoiphantichhoalysinhvn@gmail.comLê Thị Hàhoiphantichhoalysinhvn@gmail.com<p>In this study, the accumulation levels of copper in the biomass of certain herbs, including oregano, celery, <br>gotu kola, and purple perilla when grown on contaminated copper soil, were investigated. The results <br>showed that copper had the potential to accumulate in plants, with the highest accumulation in the roots, <br>decreasing in the stems and leaves. When grown in copper contaminated soil ranging from 50 to 1500 ppm, <br>the accumulation of copper decreased in the following order: oregano roots (8.28 ÷ 103.05 ppm) > purple <br>perilla roots (8.14 ÷ 66.98 ppm) > gotu kola roots (6.10 ÷ 39.95 ppm) > celery roots (5.40 ÷ 31.74 ppm) > <br>oregano stems + leaves (2.59 ÷ 24.02 ppm) > purple perilla stems + leaves (3.56 ÷ 16.45 ppm) > gotu kola <br>stems + leaves (3.62 ÷ 16.74 ppm) > celery stems + leaves (1.75 ÷ 7.16 ppm). Health risk indices for adults <br>and children when using these herbs were also assessed. The THQs (Target Hazard Quotients) for copper <br>increased in the following order: celery < purple perilla < oregano < gotu kola, and THQs for children <br>were higher than those for adults.</p>2024-03-19T09:14:56+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92798SO SÁNH HẠT NANO SELEN CHẾ TẠO BẰNG BỨC XẠ CHÙM TIA ĐIỆN TỬ VÀ BỨC XẠ GAMMA VÀ ĐỘ ỔN ĐỊNH CỦA CHÚNG2024-03-19T09:38:42+07:00Vu Le Van Khanhhoiphantichhoalysinhvn@gmail.comTran Thi Thanh Ngochoiphantichhoalysinhvn@gmail.comNguyen Ngoc Duyhoiphantichhoalysinhvn@gmail.comNguyen Thi Truc Linhhoiphantichhoalysinhvn@gmail.comNguyen Thi Nhu Dunghoiphantichhoalysinhvn@gmail.comPhan Dinh Tuanhoiphantichhoalysinhvn@gmail.com<p>Trong công trình này, các hạt nano selen (SeNPs) được tạo ra bằng cách chiếu xạ sử dụng máy gia tốc <br>chùm tia điện tử và nguồn gamma Co-60. Các đặc trưng của hạt SeNPs thu được được xác định bằng cách <br>đo UV-Vis, DLS để xác định phân bố hạt theo kích thước và đo điện thế zeta. DLS cũng được đo ở các thời <br>gian bảo quản khác nhau (1 – 6 tháng) theo nhiệt độ bảo quản (4 °C và 27 °C). Kết quả thu được chỉ ra <br>rằng các hạt SeNPs được tổng hợp bằng chùm tia điện tử và chiếu xạ gamma có cùng phạm vi phân bố hạt <br>theo kích thước. Độ ổn định của hệ hạt SeNPs tạo thành trong pha lỏng bảo quản ở nhiệt độ mát (4 °C) tốt <br>hơn ở nhiệt độ phòng (27 °C).</p>2024-03-19T09:18:30+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92799PHÁT TRIỂN PHƯƠNG PHÁP XÁC ĐỊNH CHẤT CHỐNG CHÁY CƠ PHỐT PHO Ở MẪU CÁ BẰNG PHƯƠNG PHÁP QuEChERS CẢI TIẾN KẾT HỢP GC-MS/MS2024-03-19T09:38:43+07:00Bui Quang Minhhoiphantichhoalysinhvn@gmail.comPhung Thi Anh Tuyethoiphantichhoalysinhvn@gmail.comPham Thi Phuonghoiphantichhoalysinhvn@gmail.comDao Hai Yenhoiphantichhoalysinhvn@gmail.com<p>Chất chống cháy cơ phốt pho được sử dụng rộng rãi như hợp chất ngăn chặn sự cháy trong nhiều lĩnh vực, <br>đặc biệt là ngành điện – điện tử. Do đó, các hợp chất này dễ dàng phát tán ra môi trường, gây ô nhiễm đất, <br>nước, không khí và sinh vật. Tuy nhiên, các nghiên cứu phân tích hàm lượng các hợp chất chống cháy cơ <br>phốt pho ở cá biển còn chưa được quan tâm ở Việt Nam. Bằng việc cải tiến phương pháp chiết QuEChERS, <br>cụ thể là tối ưu điều kiện hóa hơi dung môi, kết hợp sắc kí khí ghép nối khối phổ hai lần, phương pháp phân <br>tích trong nghiên cứu này phù hợp để phân tích hàm lượng vết hợp chất chống cháy trong cá biển Việt Nam. <br>Dung môi hóa hơi dưới dòng khí N2 ở 1°C tối ưu được hiệu suất thu hồi của các chất nằm trong khoảng 82 <br>– 102%. Với phương pháp được phát triển, hiệu suất thu hồi của các hợp chất ở nồng độ 1, 50 và 100 ng/g <br>lần lượt dao động trong các khoảng 91,3 – 108,2%, 92,8 – 103,7% và 92,4 – 103,7%, giới hạn phát hiện và <br>giới hạn định lượng của phương pháp lần lượt từ 0,05 đến 0,10 ng/g và từ 0,15 đến 0,30 ng/g, và các giá trị<br>lệch chuẩn tương đối của độ tái lặp phương pháp đều nhỏ hơn 20%. Phương pháp được ứng dụng để phân <br>tích trên 15 mẫu cá (thuộc 5 loài, Psettodes erumei, Sillago sihama, Rastrelliger kanagurta, Decapterus <br>macarellus, Selaroides leptolepis), với hàm lượng OPFR dao động trong khoảng 39,0 – 181,5 ng/g khối <br>lượng khô. Kết quả phân tích các mẫu cá cho thấy các hợp chất có chứa clo trong cấu trúc có hàm lượng <br>lớn hơn các hợp chất chỉ chứa các chuỗi hidrocacbon.</p>2024-03-19T09:22:51+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92801THÀNH PHẦN HOÁ HỌC CỦA LÁ LOÀI MỘC LAN TIẾP2024-03-19T09:38:44+07:00Pham Van Huyenhoiphantichhoalysinhvn@gmail.comNguyen Thi Thu Hienhoiphantichhoalysinhvn@gmail.comTran Thi Ngoc Hanhhoiphantichhoalysinhvn@gmail.comNguyen Thi Dieu Thuanhoiphantichhoalysinhvn@gmail.comNguyen Huu Huong Duyenhoiphantichhoalysinhvn@gmail.comNguyen Huu Toan Phanhoiphantichhoalysinhvn@gmail.com<p>Chi Magnolia thuộc họ Magnoliaceae, phân bố ở châu Mỹ và châu Á. Nhiều loài trong chi này có giá trị<br>chữa bệnh và được đưa vào các bài thuốc dân gian. Mộc lan Tiếp (Magnolia tiepii) là một loài đặc hữu của <br>Việt Nam, hiện có rất ít các nghiên cứu về thành phần hoá học. Quá trình nghiên cứu hoá sinh thực vật đã <br>phân lập được năm hợp chất bao gồm (+)-pinorecinol (1), lariciresinol (2), blumenol A (3), <br>dehydrovomifoliol (4) và eleutheroside B (5) từ dịch chết methanol của lá loài Mộc lan Tiếp. Cấu trúc của <br>các hợp chất được làm sáng tỏ bằng các phương pháp phân tích phổ cộng hưởng từ (1D, 2D-NMR), phổ<br>khối lượng (MS), quang phổ lưỡng sắc tròn (CD) và so sánh với các dữ liệu phổ. Đây là các hợp chất lần <br>đầu tiên được công bố từ loài này.</p>2024-03-19T09:26:28+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92805KHẢO SÁT THÀNH PHẦN HÓA HỌC VÀ HOẠT TÍNH KHÁNG KHUẨN CỦA THÂN VÀ LÁ CÂY MƯỚP ĐẮNG (Momordica charantia L.)2024-03-19T09:38:45+07:00Le Thi Bachhoiphantichhoalysinhvn@gmail.comHuynh Thu Hanhhoiphantichhoalysinhvn@gmail.comPham Thi Kim Phuonghoiphantichhoalysinhvn@gmail.comLe Thi Thanh Xuanhoiphantichhoalysinhvn@gmail.comNguyen Trong Tuanhoiphantichhoalysinhvn@gmail.comPham Quoc Nhienhoiphantichhoalysinhvn@gmail.comMai Thi Thuy Duonghoiphantichhoalysinhvn@gmail.comBanh Yen Ngochoiphantichhoalysinhvn@gmail.comLam Thi Phimhoiphantichhoalysinhvn@gmail.comNguyen Thao Phuonghoiphantichhoalysinhvn@gmail.comNguyen Thi Thuy Huynhhoiphantichhoalysinhvn@gmail.comTran Hoang Binhhoiphantichhoalysinhvn@gmail.comNguyen Thi Ngoc Hong Thamhoiphantichhoalysinhvn@gmail.comNguyen Hong Yenhoiphantichhoalysinhvn@gmail.com<p>Nghiên cứu này nhằm mục đích bước đầu khảo sát hoạt tính kháng khuẩn của các cao chiết từ thân và lá <br>cây Mướp đắng, lựa chọn cao chiết có hoạt tính tốt nhất để khảo sát thành phần hóa học nhằm tìm hiểu mối <br>liên hệ giữa hoạt tính sinh học và cấu trúc hóa học của các hợp chất có trong cây Mướp đắng (Momordica <br>charantia L.). Kết quả cho thấy cao chiết ethyl acetate thể hiện hiệu quả kháng khuẩn tốt theo phương pháp <br>khuếch tán đĩa thạch trên các chủng vi khuẩn là tác nhân gây bệnh chính cho các loài thủy sản. Cao chiết <br>ethyl acetate đều kháng lại 03 dòng vi khuẩn Aeromonas hydrophila, Aeromonas dhakensis, và Vibrio <br>parahaemolyticus với giá trị MIC ≤ 0,3125 mg/mL. Kết quả bước đầu khảo sát thành phần hóa học cho <br>thấy, từ cao phân đoạn ethyl acetate của thân và lá cây Mướp đắng, 03 hợp chất đã được phân lập và nhận <br>danh là 3β,7β,25-trihydroxycucurbita-5, (23E)-dien-19-al (1), protocatechuic acid (2), và afzelin (3). Cấu <br>trúc hóa học của các hợp chất này được xác định bằng phương pháp phổ NMR và so sánh với các tài liệu đã <br>công bố. Đồng thời, hợp chất (1) và (3) phân lập được cũng cho hiệu quả kháng khuẩn tốt đối với khuẩn <br>Aeromonas hydrophila. Những kết quả này cho thấy thân và lá cây Mướp đắng là một dược liệu tiềm năng <br>chứa các hợp chất thể hiện hoạt tính kháng khuẩn tốt.</p>2024-03-19T09:32:53+07:00Bản quyền (c) https://www.vjol.info.vn/index.php/TCPTHLS/article/view/92807NGHIÊN CỨU VI NHŨ TƯƠNG DỊCH CHIẾT CÀ PHÊ XANH ROBUSTA2024-03-19T09:38:46+07:00Dinh Thi Tuhoiphantichhoalysinhvn@gmail.comPham Thi Hong Minhhoiphantichhoalysinhvn@gmail.comNgo Kim Chihoiphantichhoalysinhvn@gmail.comPham Minh Quanhoiphantichhoalysinhvn@gmail.comNguyen Hoai Linhhoiphantichhoalysinhvn@gmail.comDang Ngoc Phuonghoiphantichhoalysinhvn@gmail.comNguyen Xuan Tunghoiphantichhoalysinhvn@gmail.comDo Thuy Tienhoiphantichhoalysinhvn@gmail.com<p>Nghiên cứu tạo chiết xuất hạt cà phê xanh Robusta bằng phương pháp tạo nhũ tương nano nước-dầu-dung <br>môi thu được nhũ tương nano nước dầu chứa các chất có hoạt tính sinh học là 2,1% caffeine, tổng axit <br>chlorogenic là 40%, 1,29% dầu, ngoài ra còn có quinic, ferulic và caffeic axit. Nhũ tương nano đạt kích <br>thước 100-200 nm, PDI đạt 0,5 và thế zeta 150mV khi có phụ gia chiết chọn lọc là chất hoạt động bề mặt <br>nhũ tương hoá nhỏ hơn 1,5% tạo vi nhũ tương nano ổn định ở pH 4,5 với mật độ 1,305 g/ml và tổng CGA <br>cao hơn. Dịch chiết hạt cà phê xanh dạng nhũ tương nano được thử nghiệm hoạt tính chống oxy hoá với kết <br>quả SC50 là 68,34ppm, có hiệu quả chống lại Gr (-) P. aeruginosa, Gr (+) S. Aureus và mốc F. oxysporum <br>ở nồng độ ức chế tối thiểu MIC 0,012 - 0,025 g/ml và khả năng gây độc tế bào đối với tế bào Hep-G2 ở <br>IC50 là 31,5ppm có CS(%) là 16,11%.</p>2024-03-19T09:37:12+07:00Bản quyền (c)