FLAVONOID VÀ TRITERPENOID TỪ PHẦN TRÊN MẶT ĐẤT LOÀI BƯỚM BẠC SÀI GÒN MUSSAENDA SAIGONENSIS

Tóm tắt

Phytochemical investigation of the aerial parts of Mussaenda saigonensis led to the isolation of 6
compounds, including 3,5,6,7,8,3′,4′-heptamethoxyflavone (1), nobiletin (2), quercetin (3), -amyrin (4),
oleanolic acid (5) và maslinic acid (6). The chemical structures of the substances were determined by the
analysis of spectroscopic data and by comparing them with existing literature. All the individual substances
were documented for the first time from Mussaenda saigonensis, to the best of our understanding. The
isolated compounds were assessed for their ability to prevent the formation of nitric oxide (NO). Compounds
3, 5 showed NO inhibition with the IC50 values ranging from 34.57, to 35.55 µM while other compounds
were weak or inactive compared to the positive control L-NMMA (IC50 29.32 μM).