NGHIÊN CỨU THÀNH PHẦN HÓA HỌC VÀ HOẠT TÍNH SINH HỌC CỦA TINH DẦU LÁ VỐI (CLEISTOCALYX OPERCULATUS ROXB.) TRỒNG Ở TỈNH PHÚ THỌ

Tóm tắt

The aim of this study was to determine chemical composition, and evaluate the antioxidant and antibacterial
activities of the essential oil from leaves of Cleistocalyx operculatus Roxb. grown in Phu Tho province. The
Gas chromatography-mass spectrometry (GC-MS) analyses of the essential oil of Cleistocalyx operculatus
Roxb. leaves led to the identification of 21 components. Its major constituents were (Z)--ocimene (60.59%),
(E)--ocimene (11.96%), -pinene (9.23%) and myrcene (6,22%). Antibacterial activity assays were
performed on the essential oil using the agar well method. The results indicated that the essential oil
showed antibacterial effects against Staphylococcus aureus, Pseudomonas aeruginosa and Candida
albicans, especially Pseudomonas aeruginosa antibacterial ability was much higher than that of cefotaxime
as an antibiotic. In the DPPH assay, the essential oil exhibited antioxidant activity with EC50 were 13828
g/mL.