ỨNG DỤNG GLOBAL NATURAL PRODUCTS SOCIAL (GNPS) TRONG XÂY DỰNG MẠNG LƯỚI PHÂN TỬ GC-MS VÀ ĐÁNH GIÁ HOẠT TÍNH SINH HỌC CỦA TINH DẦU TRÀM (MELALEUCA LEUCADENDRA) TRONG VIỆC KHÁNG KIẾN LỬA ĐỎ (SOLENOPSIS INVICTA)

Tóm tắt

Reducing the consumption of synthetic insecticides and increasing the use of natural and safe products
have become the new strategies for crop protection. This study aimed to evaluate molecular
networking-based chemical components using the new molecular networking strategy based on Global
Natural Products Social (GNPS) web platform and biological activities of Melaleuca leucadendra
essential oil against red imported fire ants (Solenopsis invicta). Results indicated that various chemical
classes of this essential oil were identified, including monoterpenes and their derivatives, monoterpene
aldehydes, and phenolics. The M. leucadendra essential oil with LC50 approximately 146.58 ± 3.75
mg/mL exhibited fumigant toxicity against worker ants and also showed a significant repellent effect on
S. invicta during outdoor environmental tests. Based on the analysis results of chemical compositions
and the toxic activity against S. invicta of M. leucadendra essential oil, we suggested that the major
compound, Methyleugenol, significantly contributed to the insecticidal ability. These results could
prompt further research about natural, safe, and non-polluting insecticides for the low-income
populations of the tropics.