KHẢO SÁT THÀNH PHẦN HÓA HỌC VÀ TÁC DỤNG KHÁNG KHUẨN CỦA LÁ GIANG (Aganonerion polymorphum Pierre ex Spire) Ở BÌNH ĐỊNH

Tóm tắt

Aganonerion polymorphum leaves are one of the popular vegetables in Binh Dinh province. By
characteristic reactions, it was found that the leaves contain triterpenoid, alkaloids, steroids, cardiac
glycosides, saponins, phenolic compounds and coumarins but no flavonoids. By chromatographic
method, ursolic acid (G4) was isolated from ethyl acetate extract. The structure of this compound has
been elucidated by modern spectroscopic method: MS, 1H-NMR, 13C-NMR, HSQC, HMBC and being
compared to results published articles. Ursolic acid is a compound isolated for the first time from the
Aganonerion polymorphum leaves. In addition, ethyl acetate extract has the ability to inhibit the growth
of Staphylococcus aureus at IC50 = 195.821.55 (µg/mL) and Lactobacillus fermentum at IC50 =
186.473.50 (µg/mL).