ĐÁNH GIÁ HIỆU QUẢ CHIẾT THU HỒI MANGOSTIN TỪ VỎ QUẢ MĂNG CỤT

Tóm tắt

Mangosteen pericare makes up around 65% of the fruit weight, it contains many xanthone derivatives,
of which α - mangostin, β – mangostin and γ - mangostin counted the highest content. Number of
studies have proved that, mangostin extracted from mangosteen pericarp has some biological activities
such as antimicrobial, antifungal, anti-inflammatory, anti-oxidant and anti-cancer. This derivative is
used in the prevention and treatment of many diseases such as infections, diarrhea, and jaundice
especially in supporting cancer treatment. In this study, extraction conditions and factors affecting
mangostin extract with ethanol 50 and 96% solvents were investigated. The results showed that the
optimal extraction conditions: solvent was ethanol 96%, extraction time was 24 hours, the solid/liquid
ratio was 1: 8 (w/v) and the temperature was 40ºC. n-hexane, ethyl acetate and acetone were used to
get puried extracts with silicagel parked column chromatography. The results showed that puried
mangostin recover performance reached 70.11 and 12.06%, respectively, accountable by raw extract
and the initial raw materials.