PHÁT TRIỂN QUY TRÌNH PHÂN TÍCH AXIT PERFLUOROOCTANOIC VÀ SUNFONAT PERFLUOROOCTAN TRONG NƯỚC BẰNG PHƯƠNG PHÁP SẮC KÝ LỎNG HIỆU NĂNG CAO GHÉP ĐẦU DÒ KHỐI PHỔ HAI LẦN (HPLC-MS/MS)

Tóm tắt

This paper describes the optimization of Perfluorooctanoic acid (PFOA) and Perfluorooctane sulfonate
(PFOS) analysis in the water at trace level (ppt). Investigations include the operating parameters of the
HPLC-MS/MS system and the enrichment procedure on the solid-phase extraction using HLB
cartridge. The linear correlation coefficient of the calibration curve was good (~0.996) in the
concentration range from 50 - 500ppt. The instrumental limit of detection was 9.6ppt and 13.8ppt for
PFOA and PFOS, respectively. The concentration using SPE column allowed reducing the limit of
detection of PFOA and PFOS to be 0.11ppt (RSD=20%) and 0.17ppt (RSD=33%) with the recovery
efficiency in the range between 70% and 140% for both compounds. The procedure was applied to the
analysis some water samples showed good repeatability with RSD of about 11.4% and 21.9% for
PFOA and PFOS respectively.