INVESTIGATION OF ANTIOXIDANT AND ANTIMICROOGANISM ACTIVITIES FROM EXTRACTS OF THE SPONGE Xestospongia testudinaria

Abstract

Among the sponge species collected in Southwestern Vietnam, Xestospongia testudinaria was relatively
abundant but was less studied. Surveying the biological activities of sponges harvested at a depth of 10
m at Phu Quoc marine, Kien Giang province, gave lots of useful information. The extracts of this
sponge species showed weak inhibition for bacterial and fungal strains (MIC > 512 µg/mL). The nhexane extract exhibited two strains of Gram (-) bacteria including Staphylococcus aureus and
Salmonella enterica with the values of IC50 from 482.46±8.5 to 435.2±10.0 µg/mL. In addition, these
sponge extracts showed moderate antioxidant activity with the values of EC50 ˂ 300 µg/mL, in the
ABTS assay.