BƯỚC ĐẦU XÂY DỰNG QUY TRÌNH XÁC ĐỊNH HÀM LƯỢNG 7 HỢP CHẤT KHÁNG OXY HOÁ TRONG NHỰA BẰNG PHƯƠNG PHÁP SẮC KÝ LỎNG HIỆU NĂNG CAO

Tóm tắt

Nowadays, polymers are widely used in various fields such as food, medicine, household appliances,
packaging, etc. Most of the polymer materials are easily degraded due to the combination of free radical
reactions. Therefore, additives such as antioxidant compounds, color pigments, plasticizers, etc., have
been added during the production process. An analytical method for the determination of 7 antioxidant
compounds (irganox 1010, irganox 3114, ionox 330, irganox 1024, irganox 1035, irgafos 38, irgafos
168) in resins by ultrasonic extraction in dichloromethane solvent coupled with high-performance liquid
chromatography with diode array detector (HPLC-DAD) has been developed. The analytical method had
a wide linearity range, 0.5 -100.0 µg mL-1
, good linearity with a correlation coefficient (R2
)>0.995. The
limit of detection and limit of quantification were between 0.014 and 0.27 µg mL-1 and 0.087 and 0.88
µg mL-1
, respectively. The recovery yields at three concentrations of 0.50, 5.0 and 15.0 µg mL-1
ranged
from 85.6 to 109.7 µg mL-1
. Besides, the repeatability of the method was also checked with %RSD from
2.1 to 8.0. This method was applied to analyze 7 plastic samples on the market. Irganox 1010 and irgafos
168 were detected in all analyzed samples with with migrating concentrations ranging in this analytical
condition from 37.3 to 393 µg g-1 and from 55.8 to 894 µg g-1
, respectively.