A STUDY ON SYNTHESIS, NMR SPECTRA OF SOME AZOMETHINE COMPOUNDS CONTAINING QUINOLINE AND FUROXAN SYNTHESIZED FROM EUGENOL IN OCIMUM SANCTUM L. OIL

Tóm tắt

5,6-Dimethoxy-8-(3-methylfuroxan-4-yl)-2-methylquinoline (2) has been synthesized from eugenol, the main constituent of Ocimum sanctum L. oil, following the Döebner – Miler method in toluene – HCl heterogeneous system. The key 5,6-Dimethoxy- 8-(3-methylfuroxan-4-yl) quinoline-2-carbaldehyde (3) obtained by oxidation of compound 2 by SeO2 in dioxane solvent at 70 oC. Compound 3 was used as a key compound for further synthesis to 2 azomethines contain quinoline and furoxan moiety. The structure of the synthesized compounds was characterized by spectroscopic methods.