STUDY ON THE ANTIBACTERIAL ABILITY OF THE HYBRID MATERIAL BETWEEN PORPHYRIN AND NANO SILVER

DOI: 10.18173/2354-1059.2022-0045

  • Vu Thi Thao1
  • Ha Thi Quyen2
  • Phan Tan Khanh1
  • Bui Thi Thu Thuy1
  • Nguyen Xuan Loc1
  • Nguyen Duc Cuong1
  • Nguyen Phuong Hoai Nam1
  • D.B. Berezin3

Tóm tắt

Water-soluble porphyrins di(4-aminophenyl)-di(4-sulfophenyl)- diphenyl-porphyrin [(SO3)2-TPP-(NH2)2](TASP) and nano-silver materials (AgNPs) were successfully synthesized by chemical synthesis and green synthesis from guava leaf extracts, respectively. The silver nanoparticle size is well controlled in the range of 1.1 - 1.5 nm. Then, AgNPs\TASP hybrid materials were successfully synthesized by different mixing methods. The UV-Vis spectrum of the hybrid material depends on the AgNPs:TASP mixing ratio and still shows the Soret peaks and Q-bands characteristic of the porphyrin family and the broad absorption range from 300 - 600 nm of the silver nanoparticles initial. The results of an antibacterial test against both gram-negative and gram-positive strains on LB agar showed that all samples had different antibacterial activities. In which, the AgNPs\TASP hybrid material has better inactivation ability than silver nano for both tested bacterial strains. Besides, the presence of polypyrrole conducting polymer (PPy) has promoted the kinetics of silver ion release, which also gives outstanding antibacterial results, thereby opening the potential to fabricate hybrid materials for antibacterial applications.

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2023-09-20