SYNTHESIS, STRUCTURE OF SOME NOVEL DERIVATIVES CONTAINING BENZOXAZOLE RING FROM p-HYDROXYBENZALDEHYDE

DOI: 10.18173/2354-1059.2022-0043

  • Nguyen Hien1
  • Nguyen Trung Hieu1
  • Nguyen Thi Ngoc Mai2
  • Pham Thi Thu May3
  • Nguyen Thi Thu Hien4
  • Duong Quoc Hoan1

Tóm tắt

Six derivatives containing benzoxazole were synthesized from phydroxybenzaldehyde via four step-route in high yields. The benzoxazole cyclization step was promoted with microwave irradiation for 10 to 30 min. Free oaminophenol derivative A3 reacted with aldehydes to form benzoxazole A4a-f, but A3.HCl couldn’t due to the presence of iron (II). Their structures were elucidated with spectroscopic methods: IR, 1D, 2D NMR, and MS. 
điểm /   đánh giá
Phát hành ngày
2023-09-20
In ra
Tập. 3 Số. 67 (2022): Tháng 10 năm 2022
Chuyên mục
BAI BÁO