SYNTHESIS OF SOME BENZOTHIAZOLE ANILINE DERIVATIVES AND THEIR BIOLOGICAL ACTIVITIES

DOI: 10.18173/2354-1059.2022-0042

  • Duong Quoc Hoan1
  • Nguyen Duc Du1
  • Truong Minh Luong1
  • Nguyen Thi Thach Thao1
  • Nguyen Thi Thu Hien2

Tóm tắt

Three benzothiazole aniline derivatives 2a, 2b, and 2c were synthesized successfully by the reduction reaction of the respective nitro compound in neutral condition with Na2S2O4 in moderate yield. Structures of these derivatives were elucidated by IR, NMR, and MS analysis that referred to a strong agreement between spectral data and structures. Three compounds 2a, 2b, and 2c showed weak antioxidant, antibacterial and antifungal activities. 
điểm /   đánh giá
Phát hành ngày
2023-09-20