DETERMINATION SULPHONAMIDES RESIDUES IN FOOD BY HIGH PERFOPvMANCE LIQUID CHROMATOGRAPHY PART 2. SEPARATION AND QUANTIFICATION SULFAGUANIDINE, SULFAMETHOXYPYRIDINE, SULFADOXINE AND SULFAMETHOXAZONE IN ANIMAL FOODSTUFFS AND FOOD PRODUCTS

Abstract

Use  of  an  RP-C18  analytical  column  with  a mobile  phase  at  pH  = 4,5  enabled  excellent

chromatographic    separation  and  quantification  of  sulfadoxine  (SDO),  sulfaguanidine  (SGU),

sulfamethoxypyridine   (SMP)  and  sulfamethoxazone   (SMX)  in  animal  foodstuffs   (for  fish,

shrimp,  chicken  and  pig)  and  food  products  (frozen  shrimp,  chicken  liver  and  pig  liver). The

proposed  conditions  are  used  for  rapid  and  reliable  analytical  SDO,  SGU,  SMP  and  SMX

content  all  samples  above.  Results  was  indicated  sulphonamides  residues  in  some   samples  of

animal foodstuffs  and food  products higher than maxium residue level [2].