INVESTIGATE THE CHEMICAL COMPOSITION OF DICHLOROMETHANE FRACTION OF GENTIANA SCABRA BUNGE

Abstract

In this study, two compounds were isolated from the dichloromethane fraction
of Gentiana scabra Bunge. By analyzing 1D and 2D NMR spectra, combined to the
comparison to literatures, compound 1 was determined to be gentioxepin, a benzo-
seven membered ring compound; and compound 2 was agreed with the structure of
δ-tocopherol, a derivative of vitamin E. Until now, there was no any report of
isolation of gentioxepin from Gentiana scabra. This research contributed to clarify the
chemical compositions of this specis in Vietnam.