Water-soluble <i>N</i>-substituted Chitosan Derivative

Abstract

Many water-soluble N-substituted chitosan derivatives have been prepared having the typical -NH-CH₂- linkage. Both the Michael reaction and alkylation with monochloroacetic acid at pH 8 - 8.5 offer relatively simple ways for their synthesis. Keywords: N-carboxymethyl chitosan; N-dicarboxymethyl chitosan; N-carboxyethyl chitosan; N-carboxybutyl chitosan; N-trimethyl chitosan; 5-methylpyrolidinone chitosan AJSTD Vol.22(3) pp.261-270 (2005)